Do JuicedPatch first, that is a must. Just run the executable and put everything in the SR2 Directory; Next, follow the GOTR with JuicedPatch tutorial I mentioned earlier; Then, after ensuring it works, add the 4GB patch, ensure it works once again; Then add optional fixes like CutscenePatch or GOTR Homies Fix; Also, make sure when you're installing your optional GOTR mods, don't get conflicting mods, alot of those mods use the same file names, if you wish to use those mods together, you have to use a program like WinMerge to merge them.